Immunological particles

The optimal immobilization of any protein, antibodies or enzyme requires a polymer coating of certain properties.

For the frequently used covalent binding uses special linker or reagents (such as glutaraldehyde, carbodiimide and others), sometimes binding agents are toxic and are needed appropriate functional groups on the surface of the protein molecule and sorbent. Although covalent bond gives good stability when repeated usage of immobilized product, covalent immobilization leads to a serious loss of spefific properties of proteins, antibodies and enzymes.

Since biochemical and physical properties (for example, structure, hydrophilicity, size, charge, sensitivity and stability) are different, catalyzed reactions can be different and this leads to difficulties to extrapolate the most suitable immobilization mechanism for a specific protein and the choice of optimal reaction.

The coating we developed provides the possibility of alternative immobilization depending on the characteristics of the protein molecule.

The main method of immobilization we recommend is a highly effective direct immobilization that does not require preliminary preparation of the surface. Functional groups located on the surface allow you to firmly bind almost any protein molecules. Moreover, the basic properties and functionality of proteins are preserved without significant losses.